产品货号：
Z23775
中文名称：
PLD6抗体
英文名称：
Anti-PLD6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PLD6 Antibody |
| 指标别名 | PLD6;Mitochondrial cardiolipin hydrolase;Choline phosphatase 6;Mitochondrial phospholipase;MitoPLD;Phosphatidylcholine-hydrolyzing phospholipase D6;Phospholipase D6;PLD 6;Protein zucchini homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF,FCM,Direct ELISA |
| 基因名称 | PLD6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PLD6 recombinant protein (Position:R39-L238). |
| 计算分子量 | 28KD |
| 实际分子量 | 28KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PLD6 (phospholipase D family,member 6) is a protein-coding gene.Among its related super-pathways are choline biosynthesis III and Glycerophospholipid biosynthesis.GO annotations related to this gene include cardiolipin hydrolase activity and protein homodimerization activity.Regulates mitochondrial shape through facilitating mitochondrial fusion.During spermatogenesis,plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (By similarity).piRNAs provide essential protection against the activity of mobile genetic elements.piRNA-mediated transposon silencing is thus critical for maintaining genome stability,in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation.Has been shown to be a backbone-non-specific,single strand-specific nuclease,cleaving either RNA or DNA substrates with similar affinity (By similarity).Produces 5' phosphate and 3' hydroxyl termini,suggesting it could directly participate in the processing of primary piRNA transcripts (By similarity).Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface.Although it cannot be excluded that it can act as a phospholipase in some circumstances,it should be noted that cardiolipin hydrolase activity is either undetectable in vitro,or very low (PubMed:21397848).In addition,cardiolipin is almost exclusively found on the inner mitochondrial membrane,while PLD6 localizes to the outer mitochondrial membrane,facing the cytosol. |
| Uniprot ID | Q8N2A8 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | phospholipase D family member 6 |
| 蛋白名全称 | Mitochondrial cardiolipin hydrolase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 201164 |
相关搜索：PLD6抗体，PLD6多抗，Anti-PLD6 Antibody